Best Mouthwash and Nasal Spray for COVID-19 in Malaysia 2022

The COVID-19 Delta variant replicates to achieve high viral loads in the throat. Therefore, appropriate mouthwashes will likely reduce the viral load in the throat and thereby reducing the risk of severe disease due to the viral load in the lungs.

One of the key approaches to minimize the risk of severe COVID-19 and also transmission would be to reduce the viral load of COVID-19 virus in the saliva, throat and nose. 

Best Mouthwashes for COVID-19 according to evidence 2021

There are lots of great mouthwashes out there, and this list is by no means complete. We’ve included therapeutic mouthwashes with proven anti-COVID-19 ingredient, you can buy over the counter.

1. Betadine Mouthwash Malaysia

The antiseptic povidone-iodine has immediate virucidal effects against COVID-19 virus. There are 6 published studies on povidone-iodine for COVID-19 (

Instructions: Gargle twice a day or after having been out for prevention, and three times a day for early treatment of COVID-19. Use full strength or diluted with an equal volume of water. Gargle or rinse for at least 30 seconds.
  • CONTAINS one 240 ml bottle of Betadine Antiseptic Sore Throat Gargle for the temporary relief of occasional sore throat
  • TREAT AND RELIEVE SORE THROAT SYMPTOMS the moment you feel a sore throat coming on
  • FAST ACTING GARGLE From Betadine, the brand that has been trusted by healthcare professionals for over 50 years.

2. Betadine Throat Spray Malaysia

An alternative for those who have difficulty with gargling. Suitable for elderly customers.
  • Wide germicidal action: Viruses, Bacteria, Fungi
  • Contains Povidone-Iodine 0.45% w/v
  • Relief of throat chapping, throat pain, throat swelling, throat discomfort and hoarseness cased by inflammation of the throat

3. Betadine Nasal Spray Malaysia

Carragelose® is a sulfated polymer from red seaweed and is a unique, broadly active anti-viral compound. It is known as a gentle yet effective and safe prevention and treatment against respiratory infections. Several clinical and preclinical studies have shown that Carragelose® forms a layer on the mucosa wrapping entering viruses, thereby inactivating them, and preventing them from infecting cells. Increasing clinical evidence indicates that Carragelose® can also inactivate SARS-CoV-2. (MedRxiv 2021)

Do not confuse Betadine mouthwash and nasal spray. Betadine mouthwash contains povidone iodine whereas Betadine nasal spray contains iota-carrageenan.

4. Oral-B 7 Benefits (CetylPyridinium Chloride Mouthwash Malaysia)

A lab study demonstrated that CPC (CetylPyridinium Chloride) was highly effective against a human coronavirus (BioRxiv 2020). CPC mouthwash is also part of the FLCCC I-MASK+ protocol for the prevention and treatment of COVID-19.

Oral-B 7 Benefits Ingredients: Water, Glycerin, Flavor, Cetylpyridinium Chloride, Sodium Saccharin, Sodium Fluoride, Methylparaben, Phosphoric Acid, Sucralose, Poloxamer 407, Propylparaben, Disodium Phosphate, CI 17200, CI 42053

5. COLGATE Plax Peppermint with Cetylpyridinium Chloride

The biggest red flag on an ingredient list for mouthwash is alcohol, according to board-certified dentist Michaela Tozzi, DMD, since it can irritate the gums and oral tissue. Plus, it temporarily depletes saliva flow, which acts as the mouth's immune system. Colgate Plax is alcohol free and contains the anti-viral CPC.




Water, Glycerin, Propylene Glycol, Sorbitol, Poloxamer 407, Flavor, Cetylpyridinium Chloride, Potassium Sorbate, Sodium Flouride, Sodium Saccharin, Menthol, CI 42051. This formula does not contain ethanol.

Key Takeaways

With so many options, you might wish to choose the one which is the most easily available to you. You might even wish to use the alternating strategy where you alternate between two different mouthwashes with different active ingredients in order to optimise the effectiveness. An important reminder is to 'start early'. Do not wait for confirmatory test that might take a few days. You can follow the preventive dosage as soon as you suspect that you have been exposed or as soon as you have a sore throat.

That said, mouthwash alone cannot be used as a stand-alone strategy to prevent or treat COVID-19. You must still adhere to your local guidelines such as vaccination, face mask, hand sanitization, quarantine, social distancing and etc.

Please consult your doctor before you start to take any drug or supplement for COVID-19.


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